Blood pressure predicted effector genes
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Method
Genes were prioritized at blood pressure-associated loci by combining several types of evidence:
- Presence of a coding variant genetically associated with blood pressure in the gene
- Association of variants in the locus with DNA methylation, gene transcription, protein levels, and metabolite levels
- Association of expression level with blood pressure
- Coregulation with other genes in blood pressure-associated loci
Reference:
Large-Scale Multi-Omics Studies Provide New Insights into Blood Pressure Regulation.
Kamali Z, et al.
Int J Mol Sci. 2022 Jul 8;23(14):7557. doi: 10.3390/ijms23147557.
PMID: 35886906
Portals
md, t2d, cvd, msk, nage, a2f, ocular, cd
Weight
0
Phenotype groups
Blood pressure predicted effector genes (Kamali Z et al., 2022)