These files correspond to the GWAS summary statistics published in :
Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
Persyn E, et al.

Association analyses have been adjusted for: 
(1) age at MRI,
(2) sex,
(3) genotyping array (Affymetrix UK BiLEVE or UK Biobank Axiom Array),
(4) the UK Biobank assessment centre (Cheadle or Newcastle),
(5) the first 10 PCs,
(6) MRI head motion indicators which are mean tfMRI head motion and Mean rfMRI head motion.

# Files
GWAS_UKB_logWMHnorm.txt.gz: GWAS results for white matter hyperintensities (WMH) volume in UK Biobank (after logarithmic transformation and normalization by intracranial volume). (N=18,381)
GWAS_UKB_PC1_FA.txt.gz: GWAS results for the first principal component on fractional anisotropy (FA) measures in 48 brain regions in UK Biobank. (N=17,663)
GWAS_UKB_PC1_MD.txt.gz: GWAS results for the first principal component on mean diffusivity (MD) measures in 48 brain regions in UK Biobank. (N=17,467)

# Fields
CHROM: Chromosome
POS: Position in bp
ID: SNP ID
REF: Reference allele
ALT: Alternative allele
A1: Tested allele
AX: Non tested allele
A1_FREQ: Frequency of the tested allele
MACH_R2: MaCH imputation quality metric
TEST: Test identifier
OBS_CT: Number of samples in the regression
BETA: Regression coefficient (for A1 allele)
SE: Standard error of beta
T_STAT: t-statistic for linear regression
P: 	Asymptotic p-value for T-stat
INFO: Imputation INFO score in UK Biobank